Month: July 2025

Crave: Harnessing The Hidden Biology of Addiction and Cancer by Dr Raphael E. Cuomo, PHD.

~ Eleanor Segall ~ 2 Comments

(image: Todd Trapani, Unsplash)

Modern life surrounds us with easy dopamine triggers: sweetened coffee on every corner, endless scrolls of video, nicotine vapes disguised as fashion accessories. My research career has shown me that these cues are not merely temptations; they are biological signals that reshape metabolism, immunity, and even cancer risk. In my book, Crave: The Hidden Biology of Addiction and Cancer, I set out to explain why.

Why cravings feel hard wired

Craving evolved as a survival mechanism. In the brain, the mesolimbic pathway flags calorie dense fruit, social bonding, or safety as worth seeking. That same circuitry now lights up for ultraprocessed snacks and late night streaming. Functional MRI studies reveal identical patterns of dopaminergic surge whether volunteers anticipate nicotine or a sugary drink, and chronic exposure dulls the reward system’s sensitivity. Over time, people need stronger stimuli for the same lift, a neuroadaptation called tolerance. My laboratory group has observed that tolerance often precedes measurable changes in inflammatory biomarkers that predict cancer progression.

From appetite to oncology

The epidemiology is startling. Meta analyses link daily sugary beverage intake with elevated colorectal cancer incidence, independent of body mass. Tobacco remains the most potent modifiable carcinogen worldwide, yet nicotine pouches marketed as “clean alternatives” still activate . Adults who replace smoking with high sugar snacks trade one risk for another; insulin spikes feed oncogenic pathways. Craving is the bridge that explains these patterns.

Listening instead of suppressing

A central message of the book is that craving is not a moral failing. It is feedback. By tuning into the signal, by asking why a craving appears rather than fighting it, we can leverage biology rather than battle it. For example, a brief walk that raises heart rate for ten minutes stimulates endocannabinoids that naturally quell appetite and elevate mood. Clinical trials suggest that this micro intervention yields sharper cognitive performance than an afternoon energy drink.

Sugar Cravings and Mental Health

Craving for sugar sits at the crossroads of addiction science and mental health because sucrose triggers the same dopamine opioid cascade in the brain that reinforces nicotine and alcohol, yet the rapid glucose spikes that follow can crash into irritability and low mood, creating a loop that feels compulsive rather than indulgent.

Evidence based tools break this loop: cognitive behavioural therapy teaches people to notice the stress cue that precedes a sugar hunt, mindfulness based relapse prevention strengthens the ability to ride out urges, nutrition counselling pairs slow digesting carbohydrates with protein to steady blood glucose, and peer groups such as SMART Recovery provide social accountability when willpower fades.

Small pivots, measurable gains

Patients who swap sugary breakfasts for fiber rich protein report fewer mid morning crashes within three weeks. Continuous glucose monitoring confirms smoother glycemic curves, and inflammatory markers such as CRP trend downward after eight weeks. Similar improvements follow digital media fasts that compress social scrolling into defined windows, freeing cognitive bandwidth and reducing late night cortisol spikes that impair immune surveillance.

Practical first steps

There exist a number of science grounded experiments readers can try: hydrate before caffeine to blunt adrenal overstimulation, pair resistance exercise with a protein rich meal to modulate leptin, schedule technology free evenings to restore natural melatonin rhythms. Track how your body responds, adjust, repeat. The data you gather on yourself becomes a personalised research study with real health dividends.

Final thought

Our ancestors survived by responding to biological urges; we thrive today by understanding them. Crave offers a map from reflexive consumption to intentional living, informed by years of bench science, clinical trials, and population studies. My hope is that readers finish the book feeling empowered to decode their own signals, rewrite their relationship with desire, and protect long term health in the process.

If that resonates, I invite you to explore the full story within the pages of Crave and share your experiences. Let curiosity, not discipline alone, guide your next step. To get your copy of Crave, please see the following link: https://www.amazon.com/dp/B0F8YVNB2S

(image: Raphael E Cuomo PHD)

Suicide Prevention Lessons In UK Secondary Schools- Congratulations 3 Dads Walking!

~ Eleanor Segall ~ 2 Comments

(image: Robinson/Tim Owen/Mike Palmer/Andy Airey)

With everything going on in the world today, some stories can get missed in the flurry of competing news. However, when I saw a post by the Oli Leigh Trust, a charity in my community dedicated to suicide prevention, that suicide prevention lessons are going to be made compulsory in secondary schools, I was so happy. Department for Education (DfE) announced on Tuesday that lessons discussing suicide prevention would be compulsory in secondary schools from September 2026.

Growing up, when I had my own issues with depression and suicidal ideation as part of my bipolar disorder, mental health was not spoken about openly in schools. We know that sadly, the suicide rate in the UK and worldwide has been rising. A group of Dads, Andy Airey, Mike Palmer and Tim Owen, 3 Dads Walking, who lost their daughters Sophie, Beth and Emily to suicide came together to campaign to Sir Keir Starmer and the UK government. Heres what they told the BBC,

‘Lives will be saved. Our Voices have finally been heard. ‘ He said the trio began campaigning shortly after their first walk to raise awareness in 2021 and admitted it had at times felt “like we were swimming through treacle uphill”, but now their “voices have been heard”.

“We have covered a lot of ground, literally and figuratively, over the last few years, but to come to a point where a significant change is going to happen still feels quite unreal. I’m stunned.”

“We are really proud of what we have achieved.”

Suicide is the biggest killer of under 35’s in the UK. In their first walk, they raised nearly 1 million pounds for Papyrus charity. In their second, they walked to all 4 UK parliaments to ensure every child was taught the skills to cope with suicidal thoughts. They then met with MPs to discuss how suicide prevention could be embedded in the curriculum.

“If this is the biggest killer of our young people, why aren’t we talking about it?”

So today I say thank you and congratulations to Andy Airey, Mike Palmer and Tim Owen- three courageous men spreading light and goodness in memory of their beloved daughters. Suicide prevention is so sadly needed.

For more on 3 Dads Walking please visit their website here: https://www.3dadswalking.uk/

Please note: This is not a sponsored post, I have been inspired by the heroism of these 3 Dads.

Why Magnesium Baths Are The New Self-Care Ritual by Miranda Spears.

~ Eleanor Segall ~ 2 Comments

(image: Pexels: Gabby K)

Self care is so important, so why not try a Magnesium Bath? Magnesium baths rely upon magnesium salts (typically magnesium sulfate or magnesium chloride) dissolved in warm water to create a solution with beneficial qualities. Magnesium ions are absorbed through the skin during your soak through a physical process called transdermal absorption, which relaxes muscles by balancing nerve impulses to muscles, and it also reduces inflammation. Magnesium is also beneficial in the production of cell energy as it helps in the production of ATP and enhances the quality of sleep, due to the control of melatonin release. Here we present five evidence-based ways magnesium baths support physical recovery, skin health, mental clarity,

Deep Absorption of Minerals in Warm Baths to Revitalise Muscles

By soaking in warm water with magnesium bath flakes, you’ll be getting a concentrated dose of this vital mineral that will be absorbed directly into the skin. Magnesium ions penetrate the skin through the flakes, entering the muscles when they disrupt pain transmission and minimise the markers of inflammation. This is selective absorption and initiates recovery of active stress, therefore, heals stiffness as well as increases flexibility. The sources of tensions dissolve, and your previously tensed muscles turn into elastic cords capable of moving in any direction. Habitual soaks enhance soothing properties, so, you can live an active life, without muscle soreness.

Enhancing Mental Clarity with Sensory-Rich Immersion

Warm water helps lighten the burden of daily challenges, and magnesium gratefully taps into neurotransmitters like GABA and tones the impartiality of moods. With every deep breath of subtly scented extra essential oils or plant infusions, every breath is gets a little stronger, until you can relax deeply. You become able to go back into your environment, and you can go and do things in a purposeful manner. Recharging of the mind roots you throughout the day in a state of productivity.

Lifting the Home Spa Atmosphere

More than minerals and water are required to turn a typical bathroom into a sanctuary. You can use soft towels, controllable lights, and adornments that create an atmosphere that welcomes relaxation. Include small-scale candles on the periphery of the tub with flames that provide soft illumination. The slightest bit of greenery helps bring nature inside for relaxation.

Gentle Agents to Boost Skin Health with Nourishment

In addition to relaxing the muscles, a magnesium bath helps to give the skin a glow. The mineral helps to hydrate and repair the cells due to its ability to attract moisture to the epidermal layer. During soaking, scrub a bit with a side brush or natural sponge to scrub off dull cells, and in turn, boost circulation. Pat dry and trap moisture by using a light natural oil or serum, and the skin will absorb the nutrients. As time progresses, you will feel that your skin has become smooth already and has a healthy glow that is a result of constant renewal with the help of minerals, so your skin will feel refreshed too.

Retraining to Have Restful Sleeping Routines

Magnesium soaks in the evenings, prepare you to take a lovely, restorative sleep with the help of balancing various hormones that control your circadian rhythm. The temperature reduction when exiting the bath into cool air is an indication to your body that you should take a rest and relax. You will sleep more comfortably, more deeply, with less anxiety and you should end up waking up in a good mood.

Magnesium baths are refreshing and also spiritually enhancing. Muscles relax, minds can be more focused, skin becomes radiant, and sleep comes as easily as breathing. This habit goes beyond relaxation and becomes a specific gesture of care taken towards yourself, one that re-echoes in all the levels of your life. By doing that, every bath will become the ritual of rejuvenation, a special moment created especially in your favour where the stress of the day is washed away and health prevails.

This article was written by Miranda Spears and contains some sponsored links.

5 Steps to Finding Deeper Inner Peace by Miranda Spears

~ Eleanor Segall ~ Leave a comment

(image: Amy Treasure: Unsplash)

In a world of continuous alerts, daily stresses, and the need to be effective, inner peace can be a distant, even impossible idea, but there are still moments- tiny, little corners that speak of peace. The difficulty is to get back to that silence when life is noisy.

These are five easy and considerate steps that can be used to guide the path towards inner peace. All of them need perfection, but most importantly, they need willingness.

1.   Make Room to Pause

The sound of daily life usually overshadows what is important. It does not mean that one has to retreat or change drastically to slow down. Other times, it is just a choice of sitting down and taking a few minutes before rushing out the door or taking a walk without music or any other distractions.

Space is the process of letting the mind breathe. It is in silence that thoughts can settle. The ever-rotating motion starts to decelerate. This is where the foundation of peace is made by creating space in your busy lives.

2.   Listen to the Body

In many cases, the body narrates before the mind can comprehend. The tight shoulders, shallow breathing, and clenched jaws are indications that something is wrong inside. Peace is not only about having the right thoughts, but it is also about feeling safe and being in the body.

That is why physical awareness is important. Observing posture, breath, or tension may be a way to come back to the present. In case you live in the region/USA, somatic healing Orange County specialists can lead this type of body-based consciousness in a more comprehensive, supported manner. They are concerned with making people realise that emotions and experiences are stored in the body, and this can be the gateway to healing and permanent peace.

3.   Make Things as Simple as Possible

It is not possible to have peace in a filthy environment. Whether it is a cluttered room or a cluttered calendar, what fills your space and what fills your time is what defines your feelings on the inside. Simple does not imply giving up everything.

It is a matter of making decisions that can really promote well-being.  It can be as easy as removing two or three items that you do not need, like saying no without feeling guilty, or emptying the small drawer that has been cluttered up long ago.

All small streamlining gestures say something that life does not need to be hectic, and in most cases, there is peace beyond the clutter.           

Each small act of streamlining says something: Life does not need to be busy, and in many cases, there is peace on the other side of the clutter.

4.   Gentle Self-Honesty

Peace does not imply evading harsh realities. Actually, one of the most obvious ways to become whole is honesty, which is said in a kind way to oneself. This type of honesty is not judgmental. It is about the soft question of what you really need, or if this is how you want to live.

Truthful contemplation can raise painful feelings. It also brings clarity. And in that clarity, peace may start to grow.

5.   Find Time for Others

Life has its moments of greater meaning, the sunrise, laughing with a loved one, or doing something nice to a stranger without any reward. These are the times that make you remember that you are more than the to-do list.

Inner peace can be found by looking at meaningful moments, not urgent moments. It is the act of paying attention to what is joyful, awing, or connecting. These experiences satisfy something within that nothing in terms of productivity or distraction ever can.

The more meaningful moments are embraced, the more they increase, and in them, there comes a feeling of peace that does not rise and fall with the day.

Conclusion

Inner peace is not a place to visit. It is a soft manner of getting around in the world, of being with yourself in a kind and openhearted way.

The small moments are the beginning of peace. It is fed by being there, fed by telling the truth, and cultivated by being in touch with the body, with others, and with what is most important.

This blog was written by Miranda Spears